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In 2011 there were over 1300 new articles published on neuroblastoma in the medical literature. Join Dr Tim Cripe and his co-host Dr  Lars Wagner in a fast-paced, in-depth, and comprehensive survey of 18 of the most important papers on neuroblastoma published in 2011. Dr Cripe and Dr Wagner explore and discuss the compelling evidence reported … Continue reading →

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Join Dr Tim Cripe and his co-host Dr Lionel Chow for a fast-paced, in-depth, and comprehensive survey of 15 important recent papers on pediatric brain tumor research, addressing medulloblastoma, ependymomas, and gliomas. Dr Cripe and Dr Chow explore and discuss the compelling evidence reported on a variety of topics, including viral causes and therapeutic implications, … Continue reading →

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Dr Tim Cripe and co-hosts Dr Maureen O’Brien and Dr Raj Nagarajan interview a pediatric hematology/oncology legend, Dr. Beatrice Lampkin, who served as Division Director of Cincinnati Children’s Division of Hematology/Oncology in the 1970’s. This enlightening and inspiring discussion explores her career and her early contributions to leukemia therapy and the challenges she faced as an early leader in the field as … Continue reading →

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Today’s episode features an impressive lineup for a hot topic. Host Dr Tim Cripe warns: “If your blood isn’t boiling by the end, you weren’t listening.” Hear Tim and co-host Dr Lionel Chow discuss pediatric cancer research funding with guests Dr C. Patrick (Pat) Reynolds, Dr E. Anders (Andy) Kolb, and parent Joe McDonough. Dr Pat Reynolds … Continue reading →

LONDON — November 7, 2011 — A new clinical trial testing 177Lutetium-DOTATATE (LuDO) for relapsed neuroblastoma is due to start in the UK next year. The UK is the first country to plan a clinical trial for this new molecular radiotherapy treatment for treating relapsed high-risk neuroblastoma, although it is already used to treat rare adult neuro-endocrine … Continue reading →

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TWiPO #19 Several just-published papers in the literature relate to recent podcast episodes, and host Dr Tim Cripe and co-host Dr Lionel Chow review these interesting developments. 0:55 Hedgehog Signaling: Recent papers discussing this pathway in neuroblastoma and rhabdomyosarcoma are discussed, with implications for treatment in these tumor types with itraconozole. 6:40 Cell phone and … Continue reading →

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Host Dr Tim Cripe and co-host Dr Lionel Chow welcome special guest Dr Jeff Toretsky on TWiPO to discuss his clinical and research interest in Ewing’s sarcoma. Dr Toretsky explains the challenges of developing a clinical grade drug from a small molecule for a specific target such as EWS-FLI1. The small market for a disease … Continue reading →

Editor’s note on this note-worthy conversation: Mooki Salzman is a mother of a child diagnosed with stage 4 neuroblastoma. Mooki’s brother, Dr Yoram Unguru, is a pediatric oncologist and happens to be a leader in the field in bioethics with regard to pediatric oncology research. They were invited to present on opposite sides of the question: … Continue reading →

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Host Dr Tim Cripe and co-hosts Dr Lars Wagner and Dr Lionel Chow welcome guest Dr Giselle Sholler on this episode of TWiPO. Dr Sholler gives the background to her current research interest in neuroblastoma, and describes her nifurtimox trials and how she formed the Neuroblastoma and Medulloblastoma Translational Research Consortium (NMTRC). The physicians also … Continue reading →

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Dr Tim Cripe and co-hosts Dr Lionel Chow and Dr Lars Wagner welcome special guest Dr Stephen Lessnick for an in-depth discussion on the progress to date in understanding the genetics of Ewing’s sarcoma. The challenges of interpreting the gene expression data as well as the ethics of collecting tumor specimens for research purposes are … Continue reading →