List/Grid Tag Archives: prognostic factors
AACR 2011: A new antibody approach for neuroblastoma?
Anti-ALK antibody explored at Children’s Hospital of Philadelphia
An increasingly important research topic in neuroblastoma focuses on anaplastic lymphoma kinase (ALK) mutation or expression. At AACR there were 8 presentations on ALK and NB. While efforts are ongoing to better target the ~7% of NB cases that have an ALK mutation, now there is also compelling research on the ALK protein expression ...
SIOP 2010 ~ Neuroblastoma oral paper presented on poor prognostic features
The neuroblastoma oral papers (OP2) presented on Friday October 22, 2010 at SIOP in Boston covered a range of topics including prognostic factors, targets, and stem cell contamination. This report will focus on the presentation on prognostic significance of segmental alterations in neuroblastoma tumors.
Accumulation of segmental alterations determines progression in neuroblastoma (O024)
Neuroblastoma ...
ANR 2010: International Neuroblastoma Risk Group (INRG) Update
In 1988 an international task force was formed to standardize the risk group classification for neuroblastoma. The reason this is so important is because international studies could not be compared to each other with different patient cohorts. One “high risk” study might actually include children considered to be intermediate risk by another group, and the outcomes reported may consequently ...
