List/Grid Tag Archives: transplant
Tübingen 2012 Neuroblastoma Symposium: from bench to bedside
Sincere appreciation is extended to NB Alliance UK for inviting me to attend this meeting and providing the travel funds.
This was the fourth meeting in a series on pediatric solid tumors and the first time the focus was on neuroblastoma. It was hosted at the Children’s Hospital (Kinderklinik) in the beautiful old city of Tübingen, which is home to the top ranked German University founded in ...
ASCO 2011 ~ SIOPEN trial reveals better survival for BuMel for transplant regimen for neuroblastoma
Dr Ruth Ladenstein presents data in Plenary Session on randomized trial comparing BuMel vs CEM for transplant after Rapid COJEC induction
Considering that neuroblastoma accounts for 7% of pediatric cancers, and pediatric cancers comprises only 1% of adult cancers (that is .07% of all cancers, and high-risk NB makes up only half that number), it is really quite remarkable when highlighted presentations ...
Antibodies and other bits
Big antibody news
The “third generation” humanized anti-GD2 antibody with protein fusion of IL2 to the antibody has completed Phase I and II clinical trials for melanoma and neuroblastoma, and is now ready for use in Phase III clinical trials. The license for hu14.18-IL2 was just acquired by a small biotech in Vienna called Apeiron. The license was acquired from Merck.
Apeiron’s press ...
CNCF 2010 ~ Allogeneic (donor) stem cell transplant for neuroblastoma
New donor transplant trial open for relapsed or refractory neuroblastoma
Dr Sandeep Soni spoke at CNCF (Children’s Neuroblastoma Cancer Foundation) Parent Conference in Chicago July 10, 2010. Dr Soni is a member of the Pediatric Blood and Marrow Transplant program at Nationwide Children’s Hospital and an Assistant Professor of Clinical Pediatrics at Ohio State University College of Medicine ...
New frontline high-risk neuroblastoma trial includes MIBG transplant
Pilot study: 131I-MIBG radiotherapy with chemotherapy after induction for newly diagnosed
Dr Greg Yanik (University of Michigan) presented preliminary results of the NANT (New Approaches to Neuroblastoma Therapy) NANT-2001-02 phase 2 MIBG + CEM (131I-MIBG radiotherapy with carboplatin, etoposide, and melphalan) stem cell transplant trial on June 23rd 2010 at the Advances in Neuroblastoma Research ...
ANR 2010 ~ Treating neuroblastoma relapse with high dose MIBG and haploidentical stem cell transplant in Sweden
SEL11 (p 136) “High dose MIBG and haploidentical stem cell transplantation with cell therapy in therapy resistant neuroblastoma”
Janek Toporski presented (5 minutes) for the Swedish group in the “Clinical” session for selected posters at ANR Tuesday June 22 .
This was a very small study with only 10 patients. The purpose was to evaluate the feasibility of high dose MIBG radiation ...
ANR 2010: MIBG avidity, tandem transplant (Korea), and ch14.18 (Germany) updates
MIBG non-avid at diagnosis = better outcome?
POC39 (p. 211) Neuroblastomas with non-avid I-123 MIBG scan and negative urinary catecholamine secretion: A single institute’s experience
PL30 (p. 102) Analysis of MIBG scoring as a prognostic indicator in patients with stage 4 neuroblastoma. A Children’s Oncology Group (A3973) report
Dui Yen Soh, Sylvain Baruchel, and Meredith Irwin at Sick Kids in ...
ASCO 2010 ~ Days 1 & 2
The 2010 ASCO meeting is in full swing. Attending a meeting with more than 30,000 cancer specialists from around the world is an incredible experience and provides an unparalleled opportunity to learn about cancer. The organization, logistics, and technology displayed are absolutely mind boggling. The vast exhibitor hall has spectacular booths set up by every pharmaceutical company ever heard of. ...
